CHICAGO — Clint Hurdle said the Pittsburgh Pirates “weren’t able to get in control of any aspect of the game.”

The Chicago Cubs made the Pirates paid for that lack of command.

Starling Marte hit a two-run homer in the fourth inning but the Pirates lost to Chicago 6-2.

Pittsburgh starter Jeff Locke (2-1) gave up six runs and eight hits in 3 2/3 innings, but was far from the only Pirates player to blame for their second consecutive loss after a five-game winning streak.

“They executed off the mound, they executed in the field, they’ve executed at the plate,” Hurdle said. “They’ve out-executed us across the board and in the dugout as well.”

Dexter Fowler had three hits and two RBIs. Kris Bryant, Starlin Castro, Junior Lake and Addison Russell each had an RBI as the Cubs scored all their runs with two outs. Travis Wood (2-1) extended his solid start to the season by allowing two runs and five hits in seven innings, helping Chicago win its fourth straight.

“It’s fun to be a part of,” Wood said.

Things haven’t been as much fun for the Pirates.

In two games at Wrigley Field, the Pirates have just nine hits. They didn’t help their cause with two errors Tuesday.

“We didn’t do anything well tonight,” Hurdle said. “We’ve been playing in some streaks. We continue to say the game’s contagious and we’ve had some contagion on the other side.”

The Cubs jumped on top with three runs in the second. Russell drove in the first one with a double, and Fowler followed with a two-run single.

Chicago added an unearned run in the third. With two outs and none on, Castro reached on a throwing error by third baseman Josh Harrison and scored on a double by Lake to make it 4-0.

“I love two-out runs, man,” Cubs manager Joe Maddon said.

The Pirates cut the deficit in half on Marte’s drive to left field, but the Cubs got the runs right back in the bottom of the fourth on run-scoring singles by Bryant and Castro.

“You’ve got to be able to make pitches,” Locke said.

The Cubs also pulled off a pair of double steals in the fourth, the first time they’ve had four stolen bases in one inning since the first inning against the Montreal Expos on Aug. 23, 1997. It was just the third time Chicago had four steals in an inning.

OF Andrew McCutchen was only 1 for 4 to raise his average to .179.