CHARLOTTESVILLE, Va. — With sore knees and another game Monday night, Kyle Guy was fine playing just 25 minutes.

He did more than enough with that action, hitting five 3-pointers and scoring 17 points as No. 2 Virginia beat Pittsburgh 73-49 on Saturday for the Panthers’ 12th straight loss.

“We’re playing it smart. We’ve got a game in less than 48 hours,” Guy said, referring to Virginia’s trip to Syracuse on Monday night.

Ty Jerome added 13 points and De’Andre Hunter scored 12 for the Cavaliers (26-2, 14-2 Atlantic Coast Conference), who maintained at least a share of the lead in the ACC .

Jared Wilson-Frame scored 15 points and Au’diese Toney had 12 for Pittsburgh (12-17, 2-14).