Jake Plummer made big passes and big plays, and delivered a huge win for the Denver Broncos.

Plummer finished with 262 yards and two touchdowns and extended his streak without an interception to 17 quarters, frustrating the New England Patriots 28-20 on Sunday.

The Broncos (5-1) have made an impressive turnaround after their season-opening debacle at Miami, where they scored 10 points and Plummer looked awful.

Against New England, Plummer may have had his finest, steadiest effort in three years in Denver.

"I can't say it's any one thing," coach Mike Shanahan said. "He's in his third year. He feels comfortable with the system. I think it's a process and hopefully, he can keep it up."

Plummer hit on throws of 72 and 55 yards, and Tatum Bell finished with 114 yards to surpass the century mark for the second straight week.

The two-time defending champions looked more like a team in disarray. Down by 25, Tom Brady tried to lead the Patriots (3-3) back to pull the Patriots within 28-20 late.

New England had a chance to tie, but Brady threw three straight incompletions and after a punt, the Denver offense ran the final 31/2 minutes off the clock.

Brady went 24-for-46 for 299 yards and a touchdown in a comeback effort fitting of the two-time Super Bowl MVP.

But it was Plummer and the Broncos that ended up on top.

In Oakland, Calif., LaDainian Tomlinson became the first player since 2001 to run, catch and throw for a touchdown as the Chargers shut down a Raiders offense slowed by an injury to Randy Moss.The Chargers (3-3) hadn't won four straight in a rivalry dominated by the Raiders (1-4) since taking the first six meetings from 1960-62, when Al Davis was their defensive ends coach.Tomlinson had 140 yards rushing and 39 yards receiving. Moss injured his groin and ribs and his status was unknown for next week.

In San Antonio, Todd Peterson kicked a 36-yard field goal to win it, but only after a miss from 41 yards was negated by a holding penalty on Saints defensive end Tony Bryant.New Orleans (2-4) had tied it at 31-31 when Aaron Brooks hit Devery Henderson in the back of the end zone for a 15-yard TD with under a minute left. Michael Vick then completed four passes and ran for a first down that quickly moved the ball down the field for Atlanta (4-2).

In Kansas City, Mo., Priest Holmes ran for a touchdown and caught five passes for 100 yards, including a 60-yard catch-and-run for the go-ahead score.Santana Moss caught 10 passes for 173 yards and two touchdowns for the Redskins (3-2), who lost their second in a row after a 3-0 start. Safety Sammy Knight, who had an 80-yard fumble return for a touchdown, got a fingertip on a potential tying pass from Mark Brunell to Moss to clinch it for Kansas City (3-2).

At Tampa, Fla., Ricky Williams returned from his four-game suspension for violating the NFL's substance-abuse policy, but Michael Pittman had the big game.Pittman ran for 127 yards and a touchdown, leading Tampa Bay (5-1). Williams ran just five times for 8 yards as Tampa Bay's defense limited the Dolphins (2-3) to 64 yards rushing. The Bucs sacked Gus Frerotte four times and forced him to fumble twice.

In Chicago, Brian Urlacher had two sacks to lead the Bears over a Vikings team reeling after allegations of drunkenness and sexual misbehavior on a charter cruise last week. It was the fourth loss in five games for Minnesota.Thomas Jones rushed for 89 yards and two touchdowns on 23 carries for the Bears (2-3).

In Detroit, Chris Weinke threw a 3-yard touchdown pass to Ricky Proehl with 32 seconds left for the victory.Weinke relieved Jake Delhomme, who was knocked out of the game on the winning drive when he was hit hard by safety Kenoy Kennedy. Weinke calmly led the Panthers (4-2) down the field, completing five of seven passes for 47 yards. The Lions (2-3) got the ball back at midfield with 24 seconds left, but couldn't complete a pass.

In Irving, Texas, Jose Cortez kicked a 45-yard field goal to help the Cowboys (4-2) overcome four turnovers and two missed field goals.Eli Manning, who struggled all game, led the Giants on two long fourth-quarter drives. The first was killed when rookie Brandon Jacobs fumbled at the Dallas 1. But New York (3-2) got the ball back and drove the Giants 52 yards to a tying TD on a 24-yard pass to Jeremy Shockey with 19 seconds left in regulation.

At Orchard Park, N.Y., Kelly Holcomb threw two touchdown passes in winning his second straight start and Willis McGahee had a career-high 143 yards rushing and a score for Buffalo (3-3).The Bills defense had five sacks and forced three turnovers. Holcomb finished 18-of-26 for 172 yards. Curtis Martin led the Jets with a season-high 148 yards rushing and became the seventh player to gain 17,000 yards from scrimmage.

In Nashville, Tenn., Carson Palmer tossed a 15-yard touchdown pass to Chad Johnson with 4:19 left that gave Cincinnati the lead for good, and the Bengals bounced back from their first loss.The Titans (2-4) had won nine of the last 10 in this series between old AFC Central rivals, but Cincinnati (5-1) won for the first time since the 2001 season finale.

In Baltimore, the Ravens forced three turnovers and sacked former teammate Trent Dilfer four times.Todd Heap scored the only touchdown for the Ravens (2-3), who bounced back from their worst start in franchise history after being penalized 21 times last week in a defeat at Detroit. Dilfer had led the Ravens to a win in the 2001 Super Bowl, but was released after the season when Baltimore opted to sign Elvis Grbac. He was obtained this year from Seattle by the Browns (2-3).

In Seattle, Seahawks running back Shaun Alexander's four touchdown runs dropped the NFL's only winless team to 0-5.The NFC West-leading Seahawks (4-2) set a franchise record with 320 yards rushing. Alexander ran for 141, and his backup, Maurice Morris, added 104.