PITTSBURGH — New research on Marcellus Shale gas drilling in Pennsylvania may only add fuel to the debate over whether the industry poses long-term threats to drinking water.

A paper published on Monday by Duke University researchers found that gas drilling in northeastern Pennsylvania did not contaminate nearby drinking water wells with salty water, which is a byproduct of the drilling.

“These results reinforce our earlier work showing no evidence of brine contamination from shale gas exploration,” said Robert Jackson, director of Duke’s Center on Global Change and a co-author of the paper, which appeared online in the Proceedings of the National Academy of Sciences. The team evaluated 426 samples from groundwater aquifers in six counties.

The findings are noteworthy because last year the same Duke team found evidence that methane from gas wells had contaminated drinking water in Pennsylvania. That prompted harsh criticism from the top official at the state Department of Environmental Protection, who accused the researchers of bias and shoddy science.

Department of Environmental Protection spokesman Kevin Sunday said the agency was still reviewing the new study, but an industry group welcomed the results.

“This research demonstrates that freshwater aquifers in northeastern Pennsylvania have not been impacted by natural gas development activities,” said Kathryn Klaber, president of the Marcellus Shale Coalition.

Environmentalists have claimed the brine water that comes up with the gas, the gas itself or the chemicals could pollute drinking water aquifers. The industry and many officials say the practice is safe when done properly, but there have also been cases where faulty wells did cause pollution.

Avner Vengosh, the new paper’s lead author, said researchers are still in the early stages of understanding the links among reservoirs of deep brine, surface aquifers and gas drilling. The industry has claimed that the final drilling takes place so far underground that fluids could never reach the surface.

But Vengosh said the research found that naturally-occurring pathways can bring the brine up into shallow aquifers, especially at the bottom of valleys. That could mean some areas are naturally more at risk of contamination from drilling, he said.

One groundwater expert said some, but not all, of the Duke findings seem to match existing research. But David Wunsch, Delaware’s state geologist, also said the Duke team’s claim that the shallow brine is coming from deep underground may be too simplistic.