DERA ISMAIL KHAN, Pakistan — Pakistan's Taliban chief Baitullah Mehsud, who led a violent campaign of suicide attacks and assassinations against the Pakistani government, has been killed in a U.S. missile strike, a militant commander and aide to Mehsud said today.

Earlier, Foreign Minister Shah Mahmood Qureshi told reporters in Islamabad that intelligence showed Mehsud had been killed in Wednesday's missile strike on his father-in-law's house in Pakistan's lawless tribal area, but authorities would travel to the site to verify his death.

Pakistani and U.S. intelligence officials said the CIA was behind the strike. All spoke on condition of anonymity because of the sensitivity of the matter.

"I confirm that Baitullah Mehsud and his wife died in the American missile attack in South Waziristan," Taliban commander Kafayat Ullah told The Associated Press by telephone. He would not give any further details.

Mehsud's demise would be a major boost to Pakistani and U.S. efforts to eradicate the Taliban and al-Qaida.

However, Mehsud has deputies who could take his place. Pakistani intelligence officials, speaking on condition of anonymity, said Taliban commanders were already believed to be meeting in the lawless tribal areas today to choose a replacement.