Penn State players run on to the field before an NCAA college football game against Oregon, Saturday, Sept. 27, 2025, in State College, Pa. (AP Photo/Jared Freed)

The Penn State Nittany Lions have undergone a good deal of change due to how their 2025 season panned out. Longtime head coach James Franklin was axed in the midst of a six-game losing streak, leading the Nittany Lions to hire now-former Iowa State leader Matt Campbell to take over.

Here’s what Campbell’s first campaign in Happy Valley will look like.

Sept. 5: Marshall

Sept. 12: at Temple

Sept. 19: Buffalo

Sept. 26: Wisconsin*

Oct. 3: at Northwestern*

Oct. 10: USC*

Oct. 17: at Michigan*

Oct. 24: Open

Oct. 31: Purdue*

Nov. 7: at Washington*

Nov. 14: Minnesota*

Nov. 21: Rutgers*

Nov. 28: at Maryland*

*denotes Big Ten game