SPOKANE, Wash. — Washington State fired football coach Nick Rolovich and four of his assistants on Monday for refusing a state mandate that all employees get vaccinated against COVID-19, making him the first major college coach to lose his job over vaccination status.

Washington Gov. Jay Inslee, a Democrat, had set a deadline of Monday for thousands of state employees, including the Cougars’ coach, to be vaccinated. Rolovich applied for a religious exemption, which was denied Monday, Washington State athletic director Pat Chun said.

Defensive coordinator Jake Dickert will be elevated to acting coach and his first game in charge will be Saturday at home against BYU.

“This is a tough day for Washington State football,” Chun said at a news conference. “Nobody wants to be here.”

Also fired for refusing vaccination were assistant coaches Ricky Logo, John Richardson, Craig Stutzmann and Mark Weber. Chun said there may be no precedent for a team losing its head coach and so many assistants in the middle of a season.

“Our student-athletes are the biggest losers in this,” he said.

Rolovich was not immediately available for comment.

The 42-year-old Rolovich was the highest-paid state employee with an annual salary of more than $3 million in a contract that runs through 2025.