Glen Campbell poses for a portrait in Malibu, Calif., in 2011, shortly after he announced he had been diagnosed with Alzheimer's disease. The musician who had hits such as “Rhinestone Cowboy” died Tuesday.

Glen Campbell, the multiple Grammy-winning country-pop singer, guitarist and TV personality has died. He was 81.

Possessed of a crystalline tenor voice and boy-next-door good looks, Campbell sold more than 45 million records and was known for a signature string of ’60s and ’70s country music hits that included “Gentle on My Mind,” “Wichita Lineman” and “Rhinestone Cowboy.”

Campbell began to slowly draw the curtain on his prolific career after announcing that he had been diagnosed with Alzheimer’s in 2011, a battle that inspired a farewell tour, documentary and a heartbreaking final album, “Adios,” released in 2017. Campbell’s death was announced Tuesday in a post on his official website and social media accounts.

“It is with the heaviest of hearts that we announce the passing of our beloved husband, father, grandfather, and legendary singer and guitarist, Glen Travis Campbell, at the age of 81, following his long and courageous battle with Alzheimer’s disease,” the statement said.

Glen Travis Campbell was born April 22, 1936, in Billstown, a tiny community near the town of Delight, Ark., the seventh son of a seventh son.

The seeds of his career were planted at the age of 4 when he received a guitar that had been ordered from a Sears, Roebuck & Co. mail-order catalog.

By age 6, he was skilled enough to appear on local radio stations, and by 10th grade he would quit high school to pursue a music career full time.

In his 20s, Campbell arrived in West to Los Angeles, where his brisk, confident guitar work was part of Elvis Presley’s “Viva Las Vegas,” The Monkees’ “Last Train to Clarksville,” and “Pet Sounds” by the Beach Boys, with whom he would briefly go on tour as a substitute for Brian Wilson.

Campbell’s career started to move center stage with a few modest hits beginning with “Turn Around, Look at Me,” a 1961 single he recorded for Crest Records; “Kentucky Means Paradise,” a 1962 tune recorded with the Green River Boys; and “Swingin’ 12 String Guitar” as part of the Folkswingers in 1963.

His big breakthrough came in 1967 when his recording of the John Hartford tune “Gentle on My Mind” hit the No. 1 spot on the country charts and the Billboard Top 40 and earned Campbell a Grammy.

Campbell’s first two hits earned him the Country Music Association’s 1967 Entertainer of the Year award. “By the Time I Get to Phoenix” earned him three more Grammys, including album of the year in 1968.

He co-hosted a 1968 summer replacement for “The Smothers Brothers Comedy Hour,” and then hosted “The Glen Campbell Goodtime Hour,” a prime-time variety show from 1969-1972.

Along the way he appeared on the big screen, too, most notably alongside John Wayne in the original 1969 version of “True Grit.”

The 1970s found Campbell’s music reaching a wider audience, with songs such as “Rhinestone Cowboy,” followed by his second and final No. 1 hit, “Southern Nights.”