LOS ANGELES — The R-rated “Deadpool” has taken the box office by storm, annihilating records with an eye-popping $135 million from its first three days in U.S. theaters, according to comScore estimates Sunday.

The Fox film, which stars Ryan Reynolds as the foul-mouthed superhero, easily trounced last year’s record-setting $85.2 million February debut of the erotic drama “Fifty Shades of Grey.” It also became the biggest R-rated opening ever, surpassing “The Matrix Reloaded,” which opened to $91.8 million in May of 2003.

Analysts are predicting that the Tim Miller-directed film, which cost a mere $58 million to produce, could go on to make $150 million by the end of the holiday weekend. As recently as Thursday, “Deadpool” was expected to pull in only $80 million across the three days, but the Marvel comic, often a best-seller, proved its popular appeal and then some — and it didn’t have to compromise with a PG-13 rating either.

“This movie is the very definition of an expectation-buster. Nobody saw this coming,” said Paul Dergarabedian, comScore media analyst. “It doesn’t feel like a cookie-cutter superhero movie. It feels like something unique. You’ve got to sometimes take risks and go against conventional wisdom to come out a winner.”

Estimated weekend sales at U.S. and Canadian theaters:

1.“Deadpool,” $135 million

2.“Kung Fu Panda 3,” $19.7 million

3.“How to Be Single,” $18.8 million

4.“Zoolander 2,” $15.7 million

5.“The Revenant,” $6.9 million

6.“Hail, Caesar!,” $6.6 million.

7.“Star Wars: The Force Awakens,” $6.2 million

8.“The Choice,” $5.3 million

9.“Ride Along 2,” $4.1 million

10.“The Boy,” $2.9 million.