WASHINGTON — In a victory for President Barack Obama, the Senate passed bipartisan legislation Friday night to strengthen the administration’s hand in global trade talks, clearing the way for a highly unpredictable summer showdown in the House.

The vote was 62-37 to give Obama authority to complete trade deals that Congress could approve or reject, but not change. A total of 48 Republicans supported the measure, but only 14 of the Senate’s 44 Democrats backed a president of their own party on legislation near the top of his second-term agenda.

Obama hailed the vote in a statement that said trade deals “done right” are important to “expanding opportunities for the middle class, leveling the playing field for American workers and establishing rules for the global economy that help our businesses grow and hire.”

Separate legislation to prevent parts of the anti-terror USA Patriot Act from lapsing on June 1 was caught in a post-midnight showdown between a pair of Kentuckians — Majority Leader Mitch McConnell on the one hand, and presidential hopeful Rand Paul on the other.

McConnell favored renewal of a program of bulk telephone collection by the National Security Agency, while Paul was unyielding in opposition. “My filibuster continues to end NSA illegal spying,” he tweeted.

By contrast, a two-month bill to prevent a cutoff in federal highway funding cleared with ease as lawmakers covetously eyed a weeklong vacation.

Senate passage of the trade bill capped two weeks of tense votes and near-death experiences for legislation the administration hopes will help complete an agreement with Japan and 10 other countries in the Pacific region.

McConnell, who was Obama’s indispensable ally in passing the bill, said it would create “new opportunities for bigger paychecks, better jobs and a stronger economy.

“The tools it contains will allow us to knock down unfair foreign trade barriers that discriminate against American workers and products stamped ‘Made in the USA,”’ he said.

A fierce fight is likely in the House.

Speaker John Boehner supports the measure, and said in a written statement that Republicans will do their part to pass it.

But in a challenge to Obama, the Ohio Republican added that “ultimately success will require Democrats putting politics aside and doing what’s best for the country.”

Dozens of majority Republicans currently oppose the legislation, either out of ideological reasons or because they are loath to enhance Obama’s authority, especially at their own expense.

And Obama’s fellow Democrats show little inclination to support legislation that much of organized labor opposes.

In the run-up to a final Senate vote, Democratic supporters of the legislation were at pains to lay to rest concerns that the legislation, like previous trade bills, could be blamed for a steady loss of jobs.

“The Senate now has the opportunity to throw the 1990s NAFTA playbook into the dust bin of history,” said Sen. Ron Wyden, D-Ore. He referred to the North American Free Trade Agreement, blamed by many for the loss of jobs.

Like Obama, Wyden and others said this law had far stronger protections built into it.