LOS ANGELES — Doom spelled dollars at the box office as the global-disaster tale "2012" opened at No. 1 domestically with $65 million and pulled in $225 million worldwide.

The Sony Pictures action saga tells the story of a scramble to save remnants of humanity aboard giant arks as the earth's crust shifts and floodwaters pour over most of the planet. With a cast led by John Cusack, Danny Glover and Chiwetel Ejiofor, "2012" was directed by doomsday specialist Roland Emmerich.

"Disney's A Christmas Carol" slipped to No. 2 with $22.3 million, down only 26 percent from its No. 1 opening gross a weekend earlier. The Jim Carrey holiday adventure raised its 10-day total to $63.3 million.

Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com.

1. "2012," $65 million.

2. "Disney's A Christmas Carol," $22.3 million.

3. "The Men Who Stare at Goats," $6.2 million.

4. "Precious," $6.1 million.

5. "Michael Jackson's This Is It," $5.1 million.

6. "The Fourth Kind," $4.7 million.

7. "Couples Retreat," $4.3 million.

8. "Paranormal Activity," $4.2 million.

9. "Law Abiding Citizen," $3.9 million.

10. "The Box," $3.2 million.