NEW YORK — The Yankees will open and close the 2010 season against the Red Sox at Fenway Park, just the fifth time in 50 years the rivals both start and finish against each other.

Most openers are set for April 5, Major League Baseball said Tuesday. In the past 50 years, the Yankees also opened and closed against Boston in 1960, 1970, 1992 and 2005, according to STATS LLC. The only times they both started and finished in Boston were 1938 and 1950.

New York plays Boston six times in its last 10 games.