ORANGE, Calif. — The U.S. topped 4,000 coronavirus deaths in a single day for the first time, breaking a record set just one day earlier, as governors tried to ramp up the pace of vaccinations and open the line to elderly people and others.

The tally from Johns Hopkins University showed the nation had 4,085 deaths Thursday, along with nearly 275,000 new cases of the virus — evidence that the crisis is growing worse after family gatherings and travel over the holidays and the onset of winter, which is forcing people indoors.

Deaths have reached epic proportions. Since just Monday, the United States has recorded 13,500 — more than Pearl Harbor, D-Day, 9/11 and the 1906 San Francisco earthquake combined.

Overall, the scourge has left more than 365,000 dead in the U.S. and caused nearly 22 million confirmed infections. More than 132,000 people nationwide are hospitalized with COVID-19.

Britain, with one-fifth the population of the U.S., likewise reported on Friday its highest one-day count of deaths yet: 1,325. That brings the country’s toll to nearly 80,000, the highest in Europe.

Meanwhile, the number of Americans who have gotten their first shot of the COVID-19 vaccine climbed to almost 6.7 million Friday, according to the Centers for Disease Control and Prevention, a robust, one-day gain of about 800,000 after a slow start to the campaign.