NEW YORK — Defending champions Naomi Osaka and Novak Djokovic are the No. 1 seeds for singles play in the U.S. Open.

Osaka, who beat Serena Williams in last year’s final for her first Grand Slam title, recently regained the top spot in the WTA rankings from Ash Barty. Barty is the No. 2 seed, followed by Karolina Pliskova, Wimbledon champion Simona Halep and Elina Svitolina.

Williams was given the No. 8 seed Wednesday by the U.S. Tennis Association. Madison Keys, the 2017 runner-up who just won the Western & Southern Open, rounds out the top 10 seeds.