PITTSBURGH — Steelers running back Willie Parker unexpectedly did not practice Friday because of ongoing problems with his sprained left knee and is unlikely to play Sunday against the New York Giants.

Wide receiver Santonio Holmes also was held out of practice and will be deactivated Sunday after city police stopped his car and smelled burning marijuana Thursday. Holmes, a former first-round draft pick, will be charged with a marijuana-related misdemeanor count.

Holmes will be replaced by Nate Washington, who has two touchdown catches in his last two games.

Two other Steelers starters also didn't practice Friday: left tackle Marvel Smith and defensive end Aaron Smith.

Safety Troy Polamalu practiced Friday and is expected to play.