It seems fitting that the NFL’s last unbeaten team is its reigning champion.

Playing catch with his receivers while almost unchallenged by the St. Louis defense, Aaron Rodgers threw for 310 yards and three touchdowns as Green Bay romped 24-3. The Packers coasted, with all the scoring coming in the opening half.

The defending Super Bowl winners are the only 6-0 team after Detroit lost to San Francisco 25-19 in a game marred by a bumping incident between the coaches.

After the 49ers improved to 5-1 and dropped the Lions to the same record, San Francisco’s first-year coach, Jim Harbaugh, charged across the field, lifting his shirt to expose his belly to attempt a chest bump. He extended his right hand to Lions coach Jim Schwartz for a shake and slapped him on the back with his left hand.

Schwartz didn’t like what was done or said — claiming he heard an expletive — and went charging after Harbaugh. Players from both teams got in the middle of the tiff, and Harbaugh admitted, “That’s totally on me. I shook his hand too hard.”

There were no such issues at Lambeau Field, where Rodgers threw a career-long 93-yard scoring pass to Jordy Nelson among his three TD passes.

James Jones and Donald Driver also caught touchdowns from Rodgers, but the Packers weren’t particularly satisfied with their performance against the Rams (0-5).

“It’s a feeling of minor disappointment, I think, in that locker room,” Rodgers said. “We just, in the second half, offensively just struggled. The second quarter was great, we put up a lot of points. I think it’s encouraging at the same time. It‘s tough to win in this league, we’re 6-0, and have a lot of room for improvement.”

Let that serve as a warning to the rest of the league.

49ers 25, Lions 19

At Detroit, Harbaugh, a first-year NFL coach who played at Michigan, and Schwartz had to be separated more than once after Schwartz came running and lunging toward Harbaugh as both teams were going to the tunnel.

“I went to congratulate coach Harbaugh and got shoved out of the way,” Schwartz said. “I didn’t expect an obscenity at that point. Obviously, when you win a game like that, you are excited, but there is a protocol that goes with this league.”

The league said it would review the incident.

Alex Smith’s fourth-down, 6-yard pass to Delanie Walker gave San Francisco the go-ahead touchdown with 1:51 left, then David Akers kicked a 37-yard field goal. He also had a 55-yarder to end the first half and the surging 49ers had five sacks of Matthew Stafford.

Raiders 24, Browns 17

At Oakland, Calif., as the Raiders (4-2) honored their late owner, Al Davis, Jacoby Ford returned a kickoff 101 yards and Kevin Boss caught a 35-yard touchdown pass on a fake field goal against Cleveland (2-3).

Eagles 20, Redskins 13

At Landover, Md., Philadelphia snapped a four-game losing streak as the defense finally came up with some big plays, mainly Kurt Coleman’s three interceptions of Rex Grossman. Michael Vick threw for 237 yards and a touchdown.

The Eagles (2-4) beat the Redskins (3-2) for the 10th time in 12 tries at Washington as LeSean McCoy rushed for 126 yards and a score.

Pats 20, Cowboys 16

At Foxborough, Mass., Dallas fell victim to its own conservatism on offense and defense late in the game. Tom Brady threw an 8-yard touchdown pass to Aaron Hernandez with 22 seconds left to cap an 80-yard drive for New England (5-1).

Bucs 26, Saints 20

At Tampa, Fla., Josh Freeman threw for 303 yards and two touchdowns, and Earnest Graham rushed for 109 yards in place of injured starter LeGarrette Blount.

The win pulled the Bucs (4-2) into a first place tie with the Saints in the NFC South and snapped New Orleans’ four-game winning streak.

Ravens 29, Texans 14

At Baltimore, Billy Cundiff kicked five field goals and the Ravens (4-1) held Houston scoreless over the final 21 minutes. They limited Arian Foster, the 2010 rushing king, to 49 yards on 15 attempts.

Giants 27, Bills 24

At East Rutherford, N.J., Ahmad Bradshaw ran for a career-best three touchdowns and 104 yards, Lawrence Tynes kicked a 23-yard field goal with 1:32 remaining and the Giants (4-2) rebounded from a bad home loss to Seattle with a win over Buffalo (4-2).

Falcons 31, Panthers 17

At Atlanta, Michael Turner ran for 139 yards and two touchdowns for the Falcons.

Bengals 27, Colts 17

At Cincinnati, Nate Clements blocked a late field goal try that would have tied the game, and Carlos Dunlap returned a fumble 35 yards for the clinching score.

Bears 39, Vikings 10

At Chicago, Devin Hester set the tone with a 48-yard touchdown catch and scored on a career-best 98-yard kickoff return before leaving with a chest injury.

Jay Cutler threw for 267 yards and two touchdowns without an interception.