Connecticut, Pittsburgh and West Virginia all lost in a stunning night of upsets in the Big East. A number of other Top 25 teams fell, as well.

Syracuse was able to avoid a letdown against St. John's, but coach Jim Boeheim expects this season to be filled with surprises.

"This league is a very good league and you better be ready every night," Boeheim said of the Big East. "There could be a lot of nights like this during the season."

Craig Smith scored 16 points, including the game-winning free throw with 35 seconds left, to lift No. 25 Boston College to a 75-70 victory over No. 10 Connecticut.

"We're not going to let people come and beat on us," Smith said. "We're going to put the beating on them."

At Pittsburgh, Brandon Bowman drove the lane for the go-ahead basket with 8.4 seconds remaining. The No. 16 Panthers then failed twice to get off a shot in a 67-64 loss to Georgetown - the second straight game they've been upset.

Allan Ray scored 26 points in Villanova's 84-46 rout of No. 21 West Virginia, snapping the Mountaineers' season-opening 10-game winning streak.

"It kind of gives them a feeling of what we can be," Villanova coach Jay Wright said. "I don't think they're shocked, but I think they're feeling real good about it."

In other upsets involving ranked teams, Michigan edged No. 14 Iowa 65-63, Houston topped No. 17 Louisville 70-67, and Vanderbilt beat Alabama 70-56.

At Hartford, Conn., Jared Dudley had a team-high 17 points for the Eagles (12-0), who are off to the best start in school history. It was the third win in 12 meetings at the Hartford Civic Center for Boston College.

"Boston College came in and took the game away from us," UConn coach Jim Calhoun said.

Josh Boone had 18 points and 15 rebounds for Connecticut (8-2).

At Villanova, Pa., Curtis Sumpter scored 13 points for the Wildcats (8-1), who won their seventh straight and had their largest margin of victory ever in a Big East game.

"This was a big step for our team," Mike Nardi said. "We're really trying to build something here."

D'or Fischer scored 14 points for the Mountaineers (10-1), who hadn't scored fewer than 70 points this season and had their season-opening winning streak stopped.

"We're certainly not a juggernaut of a 10-0 team, and we proved that today," coach John Beilein said.

At Champaign, Ill., James Augustine tied his career high with 21 points for Illinois (15-0), which used an 13-7 run at the start of the second half to take control.Tony Stockman scored 19 points for the Buckeyes (11-3).

At Lawrence, Kan., Alex Galindo hit a tiebreaking 3-pointer, and Christian Moody and Aaron Miles each made two free throws in the final seconds to lift Kansas (10-0).

At Durham, N.C., J.J. Redick made all 14 of his free throws and scored 21 points, helping Duke improve to 10-0 for the fourth time in five seasons.

At New York, Hakim Warrick scored 22 points and Gerry McNamara added 19 for Syracuse (14-1), which opened Big East play with its 36th consecutive win over an intrastate opponent.Daryll Hill had 23 points for the Red Storm (6-5), who had a three-game winning streak snapped.

At Lexington, Ky., Kelenna Azubuike made four 3-pointers and finished with 21 points as Kentucky (10-1) won its league opener for the 17th time in 18 years, beating South Carolina (8-4).

At Iowa City, Iowa, Brent Petway scored 14 points and Michigan (9-5) held off a fierce second-half rally.Pierre Pierce led the Hawkeyes (12-2) with 15 points.

Andre Owens scored 27 points, including a 3-pointer for the go-ahead basket with 21 seconds left in the first win over a Top 25 team for the Cougars (9-3) since they beat then-No. 25 Tulsa on Dec. 4, 1996.Juan Palacios had 20 points for visiting Louisville (11-3), which lost to Houston for the first time since Feb. 21, 1993.

At Starkville, Miss., Lawrence Roberts had 19 points and 15 rebounds for Mississippi State (13-2).

At Nashville, Tenn., Mario Moore shot 4-of-5 from 3-point range and finished with 16 points for Vanderbilt (10-4).Jermareo Davidson tied his career high with 21 points for Alabama (11-3).

At State College, Pa., Alan Anderson scored 17 points to lead Michigan State (9-2).Geary Claxton scored a career-high 20 points for the Nittany Lions (6-8).