WASHINGTON — Senators gave final congressional approval Thursday to a bill barring imports from China’s Xinjiang region unless businesses can prove they were produced without forced labor, overcoming initial hesitation from the White House and what supporters said was opposition from corporations.

The measure is the latest in a series intensifying U.S. penalties over China’s alleged systemic and widespread abuse of ethnic and religious minorities in the western region, especially Xinjiang’s predominantly Muslim Uyghurs. The Biden administration also announced new sanctions Thursday targeting several Chinese biotech and surveillance companies, a leading drone manufacturer and government entities for their actions in Xinjiang.

The Senate vote sends the bill to President Joe Biden. Press secretary Jen Psaki said this week that Biden supported the measure, after months of the White House declining to take a public stand on an earlier version of the legislation.

The United States says China is committing genocide in its treatment of the Uyghurs. That includes widespread reports by rights groups and journalists of forced sterilization and large detention camps where many Uyghurs allegedly are compelled to work in factories.

China denies any abuses. It says the steps it has taken are necessary to combat terrorism and a separatist movement.

The U.S. cites raw cotton, gloves, tomato products, silicon and viscose, fishing gear and a range of components in solar energy as among goods alleged to have been produced with the help of the forced labor.

Xinjiang is a resource-rich mining region, important for agricultural production, and home to a booming industrial sector. Detainees also are moved outside Xinjiang and put to work in factories, including those in the apparel and textiles, electronics, solar energy and automotive sectors, the U.S. says.

“Many companies have already taken steps to clean up their supply chains. And, frankly, they should have no concerns about this law,” Sen. Marco Rubio, the Florida Republican who introduced the earlier version of the legislation with Oregon Democratic Sen. Jeff Merkley, said in a statement.

“For those who have not done that, they’ll no longer be able to continue to make Americans — every one of us, frankly — unwitting accomplices in the atrocities, in the genocide that’s being committed by the Chinese Communist Party,” Rubio said.

As in the House earlier this week, the compromise version passed the Senate with overwhelming approval from Democrats and Republicans. The swift passage came after what supporters said was offstage opposition from corporations with manufacturing links to China, although there was little to no overt opposition.

The legislation requires government agencies to expand their monitoring of the use of forced labor by China’s ethnic minorities. Crucially, it creates a presumption that goods coming from Xinjiang are made with forced labor. Businesses will have to prove that forced labor, including by workers transferred from Xinjiang, played no part in a product to bring it into the United States.

Meanwhile, new sanctions Thursday from the Commerce Department targeted China’s Academy of Military Medical Sciences and its 11 research institutes that focus on using biotechnology to support the Chinese military.

The move bars American companies from selling components to the entities without a license.

China “is choosing to use these technologies to pursue control over its people and its repression of members of ethnic and religious minority groups,” Commerce Secretary Gina Raimondo said in a statement. “We cannot allow U.S. commodities, technologies, and software that support medical science and biotechnical innovation to be diverted toward uses contrary to U.S. national security.”