HOUSTON — Kris Bryant hit a two-run homer, Jon Lester threw seven scoreless innings and Hector Rondon and Aroldis Chapman finished off the Chicago Cubs’ 2-0 victory over the Houston Astros on Friday night.

It was Bryant’s first career game against the team that passed on him with the first pick in the 2013 draft to take starter Mark Appel, who was traded to Philadelphia this offseason before ever playing in the majors. Bryant, taken second in that draft, gave Houston an up-close look at what could have been when he smacked his 37th homer off Joe Musgrove (2-4) to put the Cubs up 2-0 in the fifth inning.

Lester (16-4) allowed seven hits and struck out seven for his seventh straight win. He hasn’t lost since July 3, hasn’t allowed a run in three of those starts and gave up just one run in four others in that span. Rondon took over for the eighth and struck out two before Aroldis Chapman struck out one in a perfect ninth for his 13th save. The Cubs are major league-best 90-50.

Marlins 4, Dodgers 1

Jose Fernandez tied a career high with 14 strikeouts, overshadowing Clayton Kershaw’s return from injury in Miami’s victory over Los Angeles.

Fernandez (14-8) gave up three hits and three walks in seven shutout innings. It was the fifth time he has struck out 14, and third this season. Kershaw (11-3) had not started for the Dodgers since June 26 because of a mild disk herniation in his back. He threw 66 pitches, 46 for strikes, and allowed two runs and five hits over three innings. The three-time Cy Young Award winner and 2014 NL MVP struck out five and did not walk a batter.

J.T. Realmuto homered for Miami, which improved to 5-0 against the NL West leaders this season. Yasmani Grandal hit his 25th homer in the ninth for the Dodgers, who tried to rally against Fernando Rodney before A.J. Ramos came in and closed it out for his career-best 33rd save.