PITTSBURGH — Rookie Jesse Winker homered for the second straight game, hitting a tiebreaking drive in the seventh inning off newly acquired Pittsburgh reliever Joaquin Benoit that sent the Cincinnati Reds over the Pittsburgh Pirates 5-2 on Wednesday night.

Adam Duvall homered and drove in three runs for the Reds. The Pirates have lost eight of 10 following a six-game winning streak.

After Pittsburgh tied it in the sixth, Winker hit a solo shot over the right-field wall with one out in the seventh to give Cincinnati a 3-2 lead. Benoit (1-5) took over to begin the seventh after being traded from Philadelphia to the Pirates on Monday.

Duvall hit his 24th homer in the ninth, a two-run drive. He earlier had a sacrifice fly.

Michael Lorenzen (6-2) won in relief of Robert Stephenson, who allowed one run in 5 2/3 innings. Raisel Iglesias closed for his 18th save.

Duvall hit a sacrifice fly to give the Reds a 1-0 lead in the fourth and Tucker Barnhart walked with the bases loaded to make it 2-0 in the sixth. Pirates starter Trevor Williams gave up two runs and six hits in 5 1/3 innings.

Josh Bell and David Freese hit RBI singles in the Pirates sixth.

The Pirates have particularly struggled with the last-place Reds, who could sweep Pittsburgh for the second time in three series this season with a win Thursday.

Cincinnati is 8-1 against Pittsburgh this year.

Trainer’s room

Reds: CF Billy Hamilton went 1 for 5 after leaving Tuesday’s game with an apparent ankle injury.

Pirates: RF Gregory Polanco was reinstated from the 10-day disabled list after missing nine games.