PARIS — Roger Federer was the last man to beat Novak Djokovic on a tennis court, and he can be the next one as well.

The 16-time Grand Slam champion set up a delectable semifinal match against the second-seeded Serb by defeating Gael Monfils 6-4, 6-3, 7-6 (3) Tuesday at the French Open. By beating Djokovic on Friday — if he beats Djokovic on Friday — Federer can end the two-time major champion’s perfect season and 43-match winning streak.

“It’s not the driving force behind this match, to be honest. For me, the plan is trying to get a step further and into the finals of the French Open,” said Federer, the 2009 champion at Roland Garros. “At the end of the day, that’s, for me, the big picture, and that’s why I entered the French Open. It wasn’t to stop Novak.”

Defending women’s champion Francesca Schiavone and No. 11 Marion Bartoli also reached the semifinals Tuesday, while Andy Murray advanced to the quarterfinals by finishing off Viktor Troicki in a five-set match that lasted two days.

On Wednesday, Murray will play again, this time for a spot in the semifinals, when he faces Juan Ignacio Chela.