EAST RUTHERFORD, N.J. — Running back Saquon Barkley is going to miss his second straight game with an ankle injury.

Coach Pat Shurmur announced Friday that Barkley and linebackers Alex Ogletree (hamstring) and Tae Davis (concussion) will not play for the New York Giants (2-2) against the Minnesota Vikings (2-2) Sunday at MetLife Stadium.

Shurmur also said linebacker Lorenzo Carter is questionable with a neck issue.

Barkley sustained a high sprain to his right ankle against Tampa Bay on Sept. 15. He worked out with trainers on Wednesday and Thursday and was limited in practice Friday.

The Giants’ next game is at the New England Patriots on Thursday night.