HARRISBURG — Pennsylvania’s acting health secretary will resign her post and depart the Wolf administration at the end of December, the governor’s office announced Monday.

Alison Beam had served in an acting role since January, when Gov. Tom Wolf tapped her to replace Dr. Rachel Levine, who left for the Biden administration.

Beam, who had previously served as Wolf’s deputy chief of staff, guided the state’s COVID-19 pandemic response over the past year. She oversaw vaccine distribution and imposed a mask mandate for schools that was struck down by the Pennsylvania Supreme Court last week.

Keara Klinepeter, the Health Department’s executive deputy secretary, will take over as acting secretary, Wolf said.

The administration did not give a reason for Beam’s resignation.