WASHINGTON — President-elect Joe Biden on Monday tapped Obama-era officials for top national security and economic roles, signaling a stark shift from the Trump administration’s “America First” policies that disparaged international alliances and favored deregulation and tax cuts.

The picks include former Secretary of State John Kerry to take the lead on combating climate change. Biden is also expected to choose Janet Yellen, who formerly led the Federal Reserve, as the first woman to become treasury secretary.

Biden’s emerging Cabinet selections rely on veteran policymakers with deep expertise and strong relationships in Washington and global capitals. And with a roster that includes multiple women and people of color — some of whom are breaking historic barriers in their posts — Biden is fulfilling his campaign promise to lead a team that reflects the diversity of America.

The incoming president will nominate longtime adviser Antony Blinken as secretary of state, lawyer Alejandro Mayorkas as homeland security secretary and Linda Thomas-Greenfield as ambassador to the United Nations. Avril Haines, a former deputy director of the CIA, will be nominated as director of national intelligence, the first woman to hold that post. Thomas-Greenfield is Black, and Mayorkas is Cuban American.

The nominations were generally met with silence on Capitol Hill, where the Senate’s balance of power hinges on two runoff races that will be decided in January.

Kerry made climate change one of his top priorities while serving as Obama’s secretary of state, during which he also negotiated the Iran nuclear deal and the Paris climate accord. Trump withdrew from both agreements. “America will soon have a government that treats the climate crisis as the urgent national security threat it is,” Kerry said. “I’m proud to partner with the president-elect, our allies, and the young leaders of the climate movement to take on this crisis as the president’s climate envoy.”

Biden will appoint Jake Sullivan as national security adviser. At 43, he will be one of the youngest national security advisers in history.

Blinken, 58, served as deputy secretary of state and deputy national security adviser during the Obama administration and has close ties with Biden. If confirmed as secretary of state, he would be a leading force in the incoming administration’s bid to reframe the U.S. relationship with the rest of the world after four years in which Trump questioned longtime alliances.

Blinken recently participated in a national security briefing with Biden and Vice President-elect Kamala Harris and weighed in publicly just last week on notable foreign policy issues in Egypt and Ethiopia.

Blinken served on the National Security Council during President Bill Clinton’s administration before becoming staff director for the Senate Foreign Relations Committee when Biden was chair of the panel. In the early years of the Obama administration, Blinken returned to the NSC and was then-Vice President Biden’s national security adviser before he moved to the State Department to serve as deputy to Kerry.