ORCHARD PARK, N.Y. — Backup defensive lineman Justin Zimmer punched the ball out of Cam Newton's arms and the fumble was recovered by safety Dean Marlowe at the Buffalo 13 with 31 seconds remaining to secure the Bills' 24-21 win over New England..

Zack Moss scored two touchdowns rushing and the AFC East-leading Bills are off to consecutive 6-2 starts for the first time since a six-year run from 1988 to 1993. Buffalo snapped a seven-game skid against the division-rival Patriots, and beat a Bill Belichick-coaches New England team for just the sixth time in 41 meetings, going back to 2000.

New England dropped to 2-5 and has lost four in a row, matching its worst skid since 2002.

MIAMI GARDENS, Fla. — Tua Tagovailoa threw his first career touchdown pass and then let his teammates take over with a succession of big plays.The Dolphins stamped themselves as playoff contenders by earning their third consecutive win. They struck for scores 75 seconds apart on Andrew Van Ginkel's 78-yard fumble return and Jakeem Grant's team-record 88-yard punt return. They came up with four takeaways in the first half and at halftime led 28-10 despite being outgained 224-54.

CHICAGO — Drew Brees threw for two touchdowns to regain the NFL's all-time lead from Tom Brady, and Wil Lutz nailed a 35-yard field goal in overtime.The Bears' Cairo Santos booted a 51-yard field goal at the end of regulation to force the extra period.The Saints (5-2) led 23-13 early in the fourth quarter after scoring 20 consecutive points, only to have Chicago rally in the closing minutes of regulation.

SEATTLE — Russell Wilson threw four more touchdown passes, two to DK Metcalf. Wilson and Metcalf tormented San Francisco and its banged-up secondary as the top-scoring offense in the league continued to pile up points. The Seahawks (6-1) have scored at least 30 points in six of seven games.

DENVER — Drew Lock hit rookie KJ Hamler from 1 yard with no time on the clock and Brandon McManus nailed the extra point to win it. The Broncos (3-4) overcame a 24-3 deficit and rallied after being held to 60 first-half yards, including 2 on the ground.

GREEN BAY, Wis. — Dalvin Cook gained 226 yards from scrimmage and became the first Viking in over four decades to score four touchdowns in a single game.The Vikings withstood a three-touchdown performance from receiver Davante Adams, who had seven catches for 53 yards.

CLEVELAND — Derek Carr threw a 4-yard touchdown pass to Hunter Renfrow early in the fourth quarter and Daniel Carlson kicked three field goals in windy, wintry conditions along Lake Erie.Carr's strike to Renfrow with 14:53 to go was the game's only TD and helped the Raiders (4-3) bounce back after they fell apart late in last week's 45-20 loss to Tampa Bay.

CINCINNATI — After watching Giovani Bernard and Samaje Perine run for early scores, Joe Burrow threw two fourth-quarter TD passes and closed it out with a time-consuming drive.The Bengals (2-5-1) blew leads each of the previous two weeks, but Burrow would not allow it to happen again. Instead, he threw for 249 yards and the crucial late scores to snap a three-game losing streak.

KANSAS CITY, Mo. — Patrick Mahomes threw for 416 yards and five touchdowns, the Kansas City defense shut down Sam Darnold and the inept Jets offense.Tyreek Hill had 98 yards receiving and two touchdowns, Travis Kelce finished with 109 yards and another score, and Mecole Hardman and Demarcus Robinson also reached the end zone. The Chiefs (7-1) gave Andy Reid his 229th win to move into a tie with Hall of Fame coach Curly Lambeau for fifth most in NFL history.

DETROIT — Philip Rivers threw three touchdown passes in the second quarter to give Indianapolis a double-digit lead.Rivers picked apart Detroit's defense while completing 23 of 33 attempts, mostly short passes to the outside or over the middle. The 38-year-old quarterback also showed he still has some arm strength.