The novel coronavirus outbreak, which has already reshaped the professional sports landscape in Europe, prompted major changes to restrict fan access in the U.S. on Tuesday, with major decisions looming about baseball’s opening day and college basketball’s NCAA Tournament.

College games will be played without fans in Ohio and California, and given restrictions on large gatherings there and elsewhere, more disruptions to the sports calendar appear inevitable. The NCAA said it would “make decisions in the coming days” about its men’s and women’s basketball tournaments after two conferences banned fans from their championships and another canceled its tournament altogether.

The baseball season begins in just over two weeks and includes games in Seattle. Of the 29 known deaths in the U.S., 24 have been in the Seattle area, with 19 tied to a single nursing home.

The Mariners are set to host the Texas Rangers on March 26. If Major League Baseball can’t play in front of fans at a team’s home ballpark, the sport’s first preference likely would be to switch games to the visiting team’s stadium if possible, a person familiar with the deliberations told The Associated Press.

Washington Gov. Jay Inslee said the state is preparing for potentially tens of thousands of cases, based on estimates of the spread of the disease.

MLB anticipates government officials will decide whether it is safe to play in front of fans in each city. If changes to the schedule are necessary, MLB would make determinations at the point when a ballpark has been ruled out.