ST. LOUIS — Michael Wacha came close, again.

The St. Louis righty lost a no-hit bid in the ninth inning for the second time in his career, denied when pinch-hitter Colin Moran led off with a single Sunday in the Cardinals’ 5-0 win over the Pittsburgh Pirates.

“It’s just a slight disappointment because I wanted it,” Wacha said. “I’ve flirted with it a couple times. It just didn’t happen. Maybe next time.”

“I was trying to get a changeup down and away,” he said. “It ended up being middle-middle, just leaving it up in the zone. I gave him something he can handle.”

As a rookie in 2013, Wacha was one out away from a no-hitter when Washington’s Ryan Zimmerman got an infield single.

Wacha (7-1) came close to pitching the fourth no-hitter in the major leagues this season. He was in total control, striking out eight and walking two while mixing his fastball, curve and change.

Bud Smith was the last St. Louis pitcher to throw a no-hitter, doing it as a rookie in 2001 at San Diego. The last Cardinals pitcher to toss a no-hitter at home was Bob Forsch in 1983 against Montreal.

Wacha retired the first 13 batters, and the closest the Pirates had come to a hit was Josh Bell’s flyout to the warning track in the second inning until the ninth.

St. Louis catcher Francisco Pena appeared more disappointed than Wacha at missing a shot at history.

“By the sixth inning, I was thinking about it, I’m not going to lie,” Pena said. “I knew he could do it too because his pitches were working really well today.”

Moran fouled off the first three pitches before the Pirates rookie lined a clean single well over the head of second baseman Kolten Wong into right field.

“I was just trying to get a pitch somewhere near the middle of the plate,” Moran said. “And luckily, I got one I could do something with. Obviously, it was cool with the crowd standing on their feet.”

The hit signaled the end for Wacha, and the 26-year-old was pulled after 111 pitches — 119 is his career high. The crowd of 44,432 at Busch Stadium gave Wacha a standing ovation, and he received hugs from his teammates in the dugout.

St. Louis manager Mike Matheny had Wacha remain on the mound a little longer than usual so the fans could continue their cheers.

“I wanted to make sure he stood there and enjoyed it,” Matheny said. “The crowd didn’t disappoint. These are things you’ll never forget.”

Reliever Jordan Hicks gave up one hit while getting the last three outs.

Marcell Ozuna hit a grand slam on the eighth pitch of the game from Nick Kingham (2-2). In April, Kingham took a perfect game into the seventh inning against St. Louis in his big league debut before it was broken up.