CLEVELAND — Yan Gomes singled home Austin Jackson from second base with none out in the 13th inning as the Cleveland Indians rallied from five runs down to stun the New York Yankees 9-8 Friday and snatch a 2-0 lead in the AL Division Series.

Jackson drew a leadoff walk in the 13th from Dellin Betances and stole second. Gomes went to a full count before pulling his bouncer just inside the third-base bag, easily scoring Jackson. The Indians poured out of their dugout to mob Gomes, who ended the 5-hour, 8-minute thriller.

The Indians posted their biggest comeback win in postseason history, overcoming an 8-3 deficit, a terrible start by ace Corey Kluber and a potentially serious injury to slugger Edwin Encarnacion.

Francisco Lindor hit a grand slam in the sixth to rally Cleveland, right after a close call on a hit by pitch that the Yankees didn’t challenge.

New York had its chances late, but the Yankees stranded the go-ahead run at third in the ninth and 10th — and had pinch-runner Ronald Torreyes picked off second in the 11th by Gomes from the behind the plate.

Cleveland will try for a sweep in Game 3 Sunday at Yankee Stadium. Carlos Carrasco is set to start for the Indians against Masahiro Tanaka.

Astros 8, Red Sox 2

HOUSTON — Carlos Correa homered, doubled and drove in four runs, Jose Altuve got two more hits and the Houston Astros hammered the Boston Red Sox 8-2 Friday to take a commanding 2-0 lead in the AL Division Series.

George Springer also homered to back Dallas Keuchel in Houston’s second straight romp by the exact same score.

The Astros will go for a sweep in the best-of-five matchup Sunday at Fenway Park.

A day after Altuve hit three home runs in the playoff opener, he got things going with a two-out single in the first inning off Drew Pomeranz. Correa, who went 0 for 4 on Thursday, made it 2-0 when he launched a towering shot onto the train tracks atop left field.

Keuchel pitched into the sixth, allowing one run and three hits while striking out seven.

After Jackie Bradley Jr. had an RBI single in the Boston second, the Astros started to break away.

Springer hit his first postseason homer when he sent the second pitch of the third inning into the front row of the seats in right field.

A double by Alex Bregman set up an RBI single by Altuve later in the inning, making it 4-1 and ending Pomeranz’s first career postseason start after two relief appearances. The lefty kept his head down as he trudged toward the dugout after being lifted.

David Price, the starter-turned-reliever with the $217 million contract, pitched 2 2/3 scoreless innings for the Red Sox. Following his exit, Houston tacked on four runs in the sixth.

Cubs 3, Nationals 0

WASHINGTON — Kyle Hendricks outpitched Stephen Strasburg, and the Chicago Cubs opened defense of their first World Series title in 108 years by beating the Washington Nationals 3-0 on Friday in Game 1 of their NL Division Series.

Kris Bryant and Anthony Rizzo produced RBI singles in the sixth inning for the first two hits off an otherwise-dominant Strasburg. Hendricks was even better, giving up only two singles in seven strong innings.

Rizzo added an RBI double off reliever Ryan Madson in the eighth. Carl Edwards Jr. threw a perfect inning and Wade Davis finished the two-hitter for a save.

Game 2 in the best-of-five series is Saturday, with Jon Lester set to start for Chicago against fellow left-hander Gio Gonzalez.