CINCINNATI — When the game’s on the line, Bengals and Steelers fans know where the ball’s most likely going.

Both teams have dynamic duos with years of experience making the game-turning, highlight-reel plays.

For the Bengals, it’s Andy Dalton and A.J. Green. For the Steelers, it’s Ben Roethlisberger and Antonio Brown. In their season openers, the duos were at their dynamic best.

Green had 12 catches for 180 yards and a touchdown during Cincinnati’s 23-22 win at the Jets. Brown had eight catches for 126 yards and two touchdowns in Pittsburgh’s 38-16 win at Washington.

They’ll share the stage on Sunday in Pittsburgh, where both defenses know what it’s all about: Stopping those two.

“First off, Ben and I both have really talented receivers,” said Dalton, who came into the NFL along with Green in 2011.

“And then it just comes with time. I’ve been with A.J. my whole career, he’s been with Antonio for seven years now. So it’s just part of the chemistry and building it.

“When you’ve got talented players, you get that chemistry. When you’re both trying to be good at what you do, you’re going to have big plays.”

Each does it their own way.

Brown has a sense of what Roethlisberger is going to do when the elusive quarterback escapes the rush. That’s when the two get creative and use an instinctiveness developed during many hours of practice.

“You put in a lot of time and a lot of hard work, a lot of film, a lot of communication,” Brown said. “We’re always looking to get better. We never dwell on what we did in the past.”

Brown has caught 375 passes in the past three seasons, an NFL record for a three-year span.

“He’s just got a motor,” Bengals cornerback Dre Kirkpatrick said. “You rarely see him tired. I’ve played him for five years, and I’ve never seen him bent over or nothing like that.”