SYRACUSE, N.Y. — Lamar Jackson continued his early season onslaught, throwing a long touchdown pass and running for four more scores to help No. 13 Louisville rout Syracuse 62-28 on Friday night in the Atlantic Coast Conference opener for both teams.

Jackson, the national offensive player of the week for his performance in the opener against Charlotte, a 70-14 victory, picked up right where he left off. He hit a wide-open James Quick for a 72-yard score on the game’s first play from scrimmage to put the Orange defense on its heels, and it stayed there during a first-quarter blitz by Jackson and company.

The elusive Jackson also hit Jaylen Smith for 61 yards and Jamari Staples for 55 in the opening spree. Jackson, who was rarely pressured by a Syracuse defense that was content to lay back, scored on runs of seven, 72 and 13 yards.