Carolina Panthers quarterback Cam Newton will get another shot at the Denver Broncos as the NFL regular season opens tonight.

DENVER — The 2016 NFL season starts the same way the last one ended, with Von Miller staring down Cam Newton.

Denver’s star linebacker got the best of Newton in Super Bowl 50, stripping both the football (twice) and the Lombardi Trophy from the Carolina quarterback’s grasp in the Broncos’ 24-10 win over the Panthers.

The sequel won’t feature Peyton Manning, who retired. When longtime backup Brock Osweiler signed with Houston two days after Manning’s tearful goodbye, GM John Elway embarked on a months-long search for a successor.

He didn’t find him in the draft, free agency or via trade, but right there on his roster in Trevor Siemian, a seventh-round draft pick in 2015 from Northwestern who’ll be making his first NFL start tonight.

Siemian has never thrown a pass as a pro. At least he won’t have to face star cornerback Josh Norman, who signed with the Redskins.

Instead, Siemian will square off against two rookie cornerbacks in James Bradberry and Daryl Worley.