DENVER — Peyton Manning gets to face his biggest nemesis for one more shot at glory.

Get ready for Brady-Manning XVII.

The NFL’s only five-time MVP earned one more and possibly final game against his rival by leading the Denver Broncos to a come-from-behind 23-16 win over Ben Roethlisberger and the Pittsburgh Steelers on a blustery Sunday.

That set up an AFC championship game next weekend in Denver against Tom Brady and the New England Patriots.

What a fitting feature to an 18th season for Manning that’s been equal parts trying and triumphant, filled with injuries and insults, rehab and redemption.

And yet another rescue.

Manning and Brady have squared off 16 times before, a full season’s worth of matchups between the two quarterbacks whose careers are so intertwined that a conversation about one almost has to include the other — like Bird vs. Magic or Ali vs. Frazier.

“It’ll be the Broncos vs. the Patriots,” Manning said of the AFC’s top two seeds, both 13-4. “We’ll enjoy this one tonight. I think you knew that answer was coming. To kind of quote Bill Belichick, we’ll be on to New England. But I’ll be talking about them on Wednesday.”

Football fans certainly won’t wait that long.

Brady has won 11 of the 16 meetings against Manning, but they’re 2-2 in the playoffs, including Denver’s 26-16 win in the conference championship game two years ago.

Just before kickoff Sunday, a strong wind blew over the Rocky Mountains, wreaking havoc on passes and kicks alike, although Brandon McManus tied an NFL playoff record by converting all five of his field-goal attempts and Chris Boswell made all three of his.

Manning’s teammates dropped seven passes but also came through in crunch time. Denver is 10-3 in games decided by seven points or fewer, and Manning said being battle-tested helped them on this blustery night

With Denver down 13-12 with less than 10 minutes left, cornerback Bradley Roby, burned time and again, punched the ball from Fitzgerald Toussaint’s arms and teammate DeMarcus Ware recovered at the Denver 35-yard line.

“Perfect timing,” Roby said.

After Toussaint’s fumble, Manning went to work, driving Denver to its only touchdown, a 1-yard run by C.J. Anderson, followed by Demaryius Thomas’ catch on the 2-pointer that put Denver ahead 20-13 with three minutes left.

That was Manning’s 55th game-winning drive in the fourth quarter or overtime, extending one of the dozen NFL records he owns.

Ware’s sack ended Pittsburgh’s next drive and McManus kicked his fifth field goal, joking it was such a tricky crosswind that he just kept aiming “at the guy holding the beer in the top left corner.”

Boswell made a 47-yarder with 19 seconds left, but Anderson recovered the onside kick.

Manning credited Denver’s NFL-best defense for thwarting a team that piled up 34 points on them last month and an offense that stayed patient.

“It was tough all night,” Manning said.