MILWAUKEE — Pittsburgh Pirates starting pitcher Wandy Rodriguez lost control right away against the Milwaukee Brewers on Monday night.

Rodriquez entered the game having walked just three batters in his first four starts on the season. He issued four walks in the first inning against the Brewers, who scored five runs in the frame on the way to a 10-4 victory.

Milwaukee pounded out five home runs and three triples along the way. Three of the home runs were hit off of Rodriguez, whose season earned-run average ballooned to 3.91 from 1.66.

“I had bad location. A lot of hitters I started behind in the count,” Rodriguez said. “For the hitter, it’s easy when they know what’s coming. When you’re behind you throw a fastball for a strike and they know a fastball is coming and they hit it.”

Rodriguez (2-1) lasted 3 2-3 innings, giving up six hits and seven runs. He walked four, struck out two and gave up three homers.

“His fastball command wasn’t what he wanted,” Pirates manager Clint Hurdle said. “We weren’t able to spot the ball, get the ball where we wanted. The breaking ball didn’t come into play until it was way too late. The change-up really wasn’t a factor. So you’re going out there without the three weapons you normally take. You’re leaving balls in the middle of the plate and you get bad results.”

Milwaukee matched a season high for runs, a day after getting shut out 2-0 by the Los Angeles Dodgers.

“We came out really aggressive. Today, everyone was swinging good,” said Brewers outfielder Carlos Gomez, who homered in the fifth. “One through nine, even the pitchers, we can drive the ball.”

Brewers pitcher Yovani Gallardo and Norichika Aoki hit consecutive homers in the fourth before Gomez and Yuniesky Betancourt repeated the feat in the fifth.

Milwaukee hit back-to-back homers twice in a game for the first time since 2005.

“We turned the page today,” said Jean Segura, whose first-inning home run put the Brewers in front 2-1. “I feel great at the plate right now, I’m relaxed and having fun.”

Gallardo (3-1) struggled with his command early but managed to settle down, tossing three-hit ball over seven innings, retiring his final 13 batters while improving to 10-2 against Pittsburgh.

He gave up two runs, one earned. He struck out five and walked two.

“I thought he struggled with his command early. Then he got the rhythm and started throwing strikes and finished outstanding,” Brewers manager Ron Roenicke said.

Milwaukee is 45-7 against the Pirates at Miller Park since 2007, the best record by any team against a division opponent during that stretch.