NEW ORLEANS — Jimmy Graham caught seven passes for a career-best 146 yards and two touchdowns, cornerback Jabari Greer made a diving, touchdown-saving pass breakup on a late fourth-down play, and the New Orleans Saints held on to hand the Atlanta Falcons their first loss, 31-27 on Sunday.

Tony Gonzalez finished with 11 catches for 122 yards and two scores for Atlanta (8-1), and in the process became the first tight end to catch 100 touchdown passes.

Brees threw for 298 yards and three TDs as the Saints (4-5) won for the fourth time in five games, keeping alive hope of getting back into the wild card race after an 0-4 start.

Texans 13, Bears 6

CHICAGO — Arian Foster finished with 102 yards rushing and a touchdown catch, and Houston intercepted Jay Cutler twice before knocking him out of the game with a concussion on their way to a soggy win.

In a showdown between two of the NFL’s best teams, the Texans (8-1) beat the Bears (7-2) at their own game. They came away with four takeaways.

49ers 24, Rams 24, OT

SAN FRANCISCO — San Francisco and St. Louis played the NFL’s first tie game in four years as kickers from both teams missed overtime field goals in Sunday’s 24-24 outcome.

The 49ers (6-2-1) lost quarterback Alex Smith to a first-half concussion.

Seahawks 28, Jets 7

SEATTLE — Russell Wilson threw touchdowns of 38 yards to Golden Tate and 31 yards to Sidney Rice, and Seattle sent the Jets to their worst start since 2007.

Cowboys 38, Eagles 23

PHILADELPHIA — Tony Romo threw a pair of touchdowns, Dwayne Harris had a 78-yard punt return for a score and Brandon Carr returned an interception 47 yards for a TD.

The Eagles (3-6) lost Michael Vick to a concussion after consecutive bruising hits in the second quarter and have lost five straight games under coach Andy Reid for the first time in his 14 seasons.

Broncos 36, Panthers 14

CHARLOTTE, N.C. — Peyton Manning made sure John Fox’s return to Carolina was a successful one, throwing for 301 yards and a touchdown.

Manning threw his 420th touchdown pass to move into a tie for second place on the NFL’s all-time list with Dan Marino.

Patriots 37, Bills 31

FOXBOROUGH, Mass. — Tom Brady threw for two touchdowns, Devin McCourty ended Buffalo’s hopes with an interception in the end zone and New England kept Buffalo winless at Gillette Stadium.

Vikings 34, Lions 24

MINNEAPOLIS — Adrian Peterson raced 61 yards for the game-sealing touchdown midway through the fourth quarter, padding his NFL rushing lead with 171 yards on 27 carries for Minnesota.

Bucs 34, Chargers 24

TAMPA, Fla. — Josh Freeman threw two touchdown passes and the surging Buccaneers scored on a blocked punt and Leonard Johnson’s 83-yard interception.

Bengals 31, Giants 13

CINCINNATI — Andy Dalton threw a career-high four touchdown passes — each to a different receiver — and the Cincinnati Bengals ended their four-game losing streak by beating the New York Giants 31-13 on Sunday.

Ravens 55, Raiders 20

BALTIMORE — Joe Flacco threw for 341 yards and three touchdowns, and Baltimore set a club record for points.

The Ravens (7-2) scored on six of their first seven possessions against the struggling Raiders (3-6), who have yielded at least 40 points in two straight games for the first time since 1962. The 55 points tied an Oakland record for points allowed, a mark set in 1961 and matched in 1981.

Titans 37, Dolphins 3

MIAMI — Colin McCarthy returned an interception 49 yards for a touchdown, and four takeaways helped Tennessee rout Miami.