Chase Utley keeps confounding Cincinnati. Doesn't matter what season, doesn't matter who he's facing on the mound.

The Phillies' power-hitting second baseman homered twice, the second a solo shot giving him 100 for his career, and Philadelphia pounded the Reds 8-4 on Friday night for its second win after an 0-2 start.

Utley hit a two-run homer off former Pirate Josh Fogg (0-1), who lasted only four innings in his Reds debut, before his milestone homer off Jeremy Affeldt. Utley is 13-for-22 in his last six games against Cincinnati, with seven homers and 13 RBI.

"To me, it's just another home run," Utley said of No. 100, which also gave him 14 career multihomer games — the last two coming against the Reds.

Pat Burrell also had a two-run homer for the Phillies. Six of their 10 hits went for extra bases.

"The last two games, we've started swinging the bat pretty good," manager Charlie Manuel said. "We need to. We have to."

Fogg, a 31-year-old right-hander with a 60-61 career record, needed 28 pitches to get through the first inning alone. Ryan Howard hit a sacrifice fly, and Burrell followed with a two-run homer.

At San Diego, Hiroki Kuroda was brilliant in his big league debut, holding San Diego to three hits in seven innings with a mix of fastballs, sliders and an occasional splitter.

At Denver, Micah Owings (1-0) struck out a career-best nine batters and allowed one run and two hits over 6X\c innings — at one point retiring 17 straight. Chad Qualls and Juan Cruz completed the two-hitter.

At Chicago, J.R. Towles homered in the fourth, Miguel Tejada added a go-ahead triple in the eighth and the Astros made a first-time winner of 23-year-old reliever Wesley Wright.

At Milwaukee, Bill Hall homered twice and had a career-high six RBI, Prince Fielder went 3-for-4 with three RBIs and Carlos Villanueva (1-0) picked up a win for the Brewers.Ex-Pirate Salomon Torres pitched three innings for his first save.

At St. Louis, Braden Looper (1-0) gave up a run and five hits in six innings to continue the Cardinals' strong starting pitching.