The Kansas City Royals got off to a great start with a record-setting first inning.

Nine innings later, they set a few more marks — ones they'd like to forget.

Ryan Garko and Hector Luna hit run-scoring singles in the 10th inning, capping the Cleveland Indians' improbable nine-run comeback in a 15-13 victory at Kansas City on Wednesday night.

The Royals' 10-1 first-inning lead was the biggest blown in a loss in franchise history, and their season-high 19 hits set the team mark for most in a defeat.

"We stopped hitting and they didn't," Kansas City manager Buddy Bell said. "It seemed like every inning they had something going on and we just could not stop them."

Cleveland scored two runs in the third, three in the fourth, one in the fifth and two in the six to pull within a run.

"They just kept creeping back, creeping back, creeping back," said the Royals' Mark Sweeney.

The Royals scored three times in the bottom of the sixth and led 13-9 going to the ninth. However, Garko, Luna and Victor Martinez hit RBI doubles off Joe Nelson to pull to 13-12. Pinch-hitter Shin-Soo Choo tied it with an RBI triple off Ambiorix Burgos, who blew his 12th save.

"The word is unbelievable," said Byrd, who was charged with nine of Kansas City's 10 first-inning runs.

Grady Sizemore was hit by a pitch from Kansas City's Andrew Sisco (1-3) leading off the 10th. He moved to second on a sacrifice and scored on Garko's two-out single to center. Luna added a run-scoring single to make it 15-13 and finished with four RBIs.

Joe Crede hit two homers and Jermaine had a three-run shot to help Chicago bounce back after losing the first two matchups of the four-game series at Detroit.

Rookie Matt Garza (1-2) allowed one unearned run in six innings to earn his first major league victory, and Michael Cuddyer had three hits and two RBIs to lead visiting Minnesota.

Jorge Cantu hit his first homer since July 29 and drove in three runs to lead host Tampa Bay.

Esteban Loaiza (7-7) pitched a four-hitter for his first shutout in more than two years, and Frank Thomas and Milton Bradley homered to lead visiting Oakland.Thomas hit his 475th homer — off Gustavo Chacin (6-3) — to tie Willie Stargell and Stan Musial for 23rd on the all-time list.

Chien-Ming Wang allowed seven hits in seven innings for his 15th victory, and Robinson Cano drove in three runs to lead New York to its sixth win in seven games — all on the road.

David Ortiz and Wily Mo Pena hit two-run homers and visiting Boston snapped a season-worst six-game losing streak.

Jimmy Rollins' clutch hit moved the Philadelphia Phillies a little closer to the top of the NL wild-card race.Rollins doubled in the go-ahead run in the ninth and the Phillies beat the Chicago Cubs 2-1 to extend their winning streak to five games.

The Padres are right back in the NL West race thanks to another sweep of their biggest rival, the suddenly rattled Dodgers.

At Cincinnati, pinch-hitter Aubrey Huff's two-run single keyed Houston's six-run seventh inning, and the Astros avoided a three-game sweep.

At New York, Jose Reyes hit a three-run homer, Chris Woodward had a three-run double and the Mets held on for the win.

Ben Sheets (4-5) pitched seven sharp innings and Prince Fielder drove in two runs for Milwaukee.

At San Francisco, rookie Eliezer Alfonzo delivered the go-ahead hit for the second straight game, and Pedro Feliz ended an 0-for-15 stretch with a tying two-run double in the seventh for the Giants.

Miguel Cabrera homered twice and drove in four runs to help the Marlins complete a three-game sweep.