Milwaukee pitcher and Seneca Valley graduate Zach Jackson gave up 10 hits but only two earned runs in 6 1/3 innings in his first major league start against San Diego Wednesday, but he didn't get the decision in the Brewers' 6-5 loss.

MILWAUKEE — It wasn't the fact that Matt Wise got beat on consecutive 0-2 pitches that irked him. It was where he threw those two pitches.

"I wouldn't take the pitches back," said the Milwaukee Brewers reliever. "Just the location."

Misplacing two 0-2 pitches cost Wise back-to-back homers by Adrian Gonzalez and Vinny Castilla in the top of the eighth inning, allowing San Diego to snatch back a 6-5 victory Wednesday night at Miller Park.

It was a discouraging loss for the Brewers, who played awful defense behind rookie lefty and Seneca Valley graduate Zach Jackson in the early going yet still were in position to win when Brady Clark socked a two-run homer off reliever Scott Cassidy in the bottom of the seventh to put the home team on top, 5-4.

The Brewers put themselves in position to need late heroics by playing hot-and-cold defense in the first half of the game. The infield helped get Jackson out of jams in the first, second and fifth innings by turning 6-4-3 double plays.

But errors by third baseman Corey Koskie in the first inning and Jackson in the second put the Brewers in a quick 2-0 hole. Bill Hall erased that lead in the bottom of the second with a two-run homer off Brewer killer Chan Ho Park but San Diego's fourth run off Jackson scored on an RBI single in the sixth by Castilla that second baseman Rickie Weeks let get by despite being perfectly positioned up the middle.

While the early miscues and Wise's misplaced pitches made it difficult for Brewers manager Ned Yost to revel in Jackson's first big-league start, he liked what he saw from the latest starter to get a chance to fill one of the rotation spots vacated by injuries to Tomo Ohka and Ben Sheets.

"Zach Jackson came out and did everything you want a young pitcher to do," said Yost. "He pitched with conviction and he was banging strikes.

"That's what we're looking for in our young pitchers, to come out and believe in themselves and give themselves a chance."

Jackson had to work out of trouble often, allowing 10 hits and a walk in 6Z\c innings. But he showed a knack for avoiding the big outbursts that plagued those who came before him from the minors.

"It was a battle," said Jackson, one of three players acquired from Toronto last winter in the Lyle Overbay trade. "I wanted to give my team a chance to win and I was able to do that."

Jackson rued making a wild throw to first on Gonzalez's bunt leading off the second, calling it a "stupid error on my part."

But Jackson was pleased with the damage-control aspect of his outing, helped in large part by keeping the ball down and getting the three double plays.

"I made some pitches whenever I had to," said Jackson, who got a standing ovation when he exited in the seventh. "It was a great experience."

The experience almost was truly memorable when Jackson appeared to sock a home run in his first major-league at-bat in the second inning but San Diego right fielder Brian Giles made a leaping catch against the wall.

"I thought I got it," said Jackson. "As it turned out, it could have turned the game around."