Even Randy Johnson couldn't stop the streaking Tampa Bay Devil Rays.

Jose Cruz Jr. hit a three-run homer and the visiting Devil Rays stretched their franchise-record winning streak to nine games with a 6-2 victory over Johnson and the Arizona Diamondbacks on Friday night.

"We're getting hits at the right time," Julio Lugo said. "I think we're going to give a hard time to anybody that faces us."

Tampa Bay won for the 20th time in 26 games and snapped Johnson's six-game winning streak in the first meeting between the 1998 expansion teams.

The Yankees and Dodgers have been rivals a lot longer than that - but they had never played in the regular season until Friday.

Los Angeles picked up right where it left off in the 1981 World Series, beating New York 6-3 behind ex-Yankee Jeff Weaver.

Playing before the largest regular-season crowd in Dodger Stadium history (55,207), the Yankees lost back-to-back games for the first time since May 21-22 at Texas.

"It was incredible," Dodgers outfielder Dave Roberts said. "I've been here for three years and I haven't seen it like this. To see the support and the excitement and the energy just filtered through the dugout, and we felt it."

In other interleague games, it was: Oakland 2, the Chicago Cubs 1; Boston 14, San Francisco 9; Seattle 5, Pittsburgh 4; the Chicago White Sox 11, Montreal 7; Kansas City 10, Philadelphia 4; the New York Mets 3, Detroit 2; Texas 8, Florida 1; Cleveland 4, Atlanta 2; Houston 5, Anaheim 0; Milwaukee 4, Minnesota 1; Colorado 5, Baltimore 3; and Toronto 3, San Diego 2.

In the only NL game, Ken Griffey Jr. failed to hit his 500th homer, and St. Louis beat Cincinnati 4-3 in 10 innings.

Juan Encarnacion drove in the go-ahead run in the sixth inning for Los Angeles. The teams hadn't played a game that meant anything since the '81 World Series, which the Dodgers won 4-2 by sweeping the final four games.

Of their 11 World Series meetings, the Yankees won eight titles. Seven of the Dodgers' appearances came when they played in Brooklyn.

Weaver (5-7), booed out of New York last season, gave up three runs in six innings. He also shut down Alex Rodriguez, who had reached base safely in 53 straight games.

"I was definitely excited about it," Weaver said. "Anytime you face the team you played with last you're looking for a little redemption to kind of show them what they might have lost."

Eric Gagne got three outs for his 17th save, extending his major league record to 80 in a row.

Yankees starter Javier Vazquez (7-5) struggled with his control and made a key throwing error.

In Phoenix, Rey Sanchez added a run-scoring triple and Geoff Blum an RBI double for the Devil Rays.

Winning pitcher John Halama (3-1) allowed two runs in five innings in his first start since Sept. 4 with Oakland. Jorge Sosa threw three scoreless innings in relief.

Johnson (9-5) was charged with five runs and eight hits in six innings. He struck out four, matching a season low.

"This was a bad game, a poorly pitched game on my part," he said. "And when you don't have your good stuff against a team that's playing well, it shows."

At St. Louis, Ken Griffey Jr. came up empty again in his bid to hit his 500th homer. He was 0-for-4, and is 3-for-17 with two RBIs in four games since he homered Sunday against Cleveland.Albert Pujols homered off Mike Matthews (1-1) to lead off the bottom of the 10th, and the Cardinals extended their winning streak to five games.

At San Francisco, pinch-hitter Kevin Millar delivered a go-ahead three-run homer in the fifth inning for Boston.David Ortiz and Manny Ramirez also homered in the fifth, and Trot Nixon and Doug Mirabelli hit back-to-back homers in the ninth for the Red Sox.Marquis Grissom homered twice for the Giants, who had their nine-game home winning streak snapped in the first regular-season meeting between two old franchises.

At Chicago, Mark Kotsay homered and drove in another run, and Oakland spoiled Sammy Sosa's return from a month on the DL.Sosa, who went 0-for-4 in his first game since May 15, had a chance to tie it with two outs in the ninth but grounded out to short to end the game.Matt Clement (7-5) gave up seven hits and two runs in eight innings.

At Pittsburgh, Jamie Moyer (6-2) pitched six solid innings and hit a two-run single, leading Seattle.Moyer struck out four, walked one and allowed three hits in his first start in Pittsburgh since May 21, 1991, when he gave up two homers to Barry Bonds while pitching for St. Louis.

At Philadelphia, Matt Stairs homered twice and Benito Santiago hit a three-run shot for Kansas City.Chris George (1-0) allowed four runs and nine hits in 6 2-3 innings, helping the Royals win their third straight.Santiago broke his left hand and will be sidelined at least six weeks after he was hit by a pitch from Geoff Geary in the sixth.

At Montreal, Carlos Lee had four hits and four RBIs, and Chicago extended the Expos' losing streak to seven.Lee, who fell a triple short of the cycle, drove in the go-ahead run in the eighth with an RBI single off Luis Ayala (0-6).

At Miami, John Wasdin (1-0) won his first start in nearly six years, Alfonso Soriano drove in two runs and Texas snapped a four-game losing streak.In his Marlins debut, Billy Koch gave up a run on two hits.

At Atlanta, Cliff Lee (6-1) outpitched Mike Hampton (1-7) to win for the first time in six starts, and Casey Blake hit a tiebreaking homer to lift Cleveland over the Braves in their first meeting since the 1995 World Series.

At New York, Mike Cameron homered with two outs in the bottom of the ninth for the Mets.Tom Glavine pitched seven solid innings in a no-decision and hit a two-run single. Richard Hidalgo, acquired the previous day from Houston, was 0-for-4 in his debut for the Mets.

At Houston, Pete Munro (1-0) combined with three relievers on a five-hitter, and Jeff Kent drove in three runs.The Astros snapped a four-game losing streak and gave manager Jimy Williams his 900th career victory.

At Milwaukee, Ben Sheets (6-4) pitched four-hit ball for six innings, and Chad Moeller homered for the Brewers, who snapped Minnesota's three-game winning streak.

At Denver, Shawn Estes (7-3) allowed two runs in seven innings for his first win in a month, and Todd Helton drove in three runs.Colorado's Preston Wilson returned after missing 58 games because of knee surgery and went 0-for-4.Rafael Palmeiro hit career homer No. 538, and Jerry Hairston was a homer short of the cycle for the Orioles, who lost their sixth straight.

At San Diego, Frank Menechino homered on David Wells' fifth pitch, and Ted Lilly (6-3) shut down San Diego, which lost its season-high sixth straight.The Blue Jays snapped their four-game losing streak.