NASHVILLE, Tenn. — The wait between games caused by the NFL’s first COVID-19 outbreak left the Tennessee Titans depleted.

They’re still undefeated.

Ryan Tannehill threw for three touchdowns and ran for another as the Titans routed the Buffalo Bills 42-16 on a rare Tuesday night in a showdown between two of the NFL’s five remaining undefeated teams pushed back two days after a couple more positive tests for Tennessee last week.

The Titans (4-0) continued their best start since winning their first 10 games in 2008 despite getting on the field the past three days since their last game Sept. 27 in Minnesota. Coach Mike Vrabel said everyone in the organization would get a game ball after this performance.

“I learned a long time ago is the definition of a pro is they make the hard look easy, so whatever situation we’re presented with we got to all come together and make the best decisions for the team each and every time,” Vrabel said.

Malcolm Butler intercepted two passes, the second he returned 68 yards, and both set up short touchdowns for Tennessee. Kareem Orr’s recovery of a fumbled kickoff set up Tannehill’s fourth TD for 21 points off Buffalo’s three turnovers.