SANTA CLARA, Calif. — Eli Manning threw a 3-yard touchdown pass to Sterling Shepard with 53 seconds left and the New York Giants snapped a five-game losing streak by beating the San Francisco 49ers 27-23 on Monday night.

Manning threw two TD passes to Odell Beckham Jr. and then engineered the late game-winning drive with help from a pair of third-down penalties against Malcolm Smith and Ahkello Witherspoon.

Saquon Barkley then had a 23-yard catch to get the ball into the red zone and Manning connected with Shepard on third down to give the Giants (2-7) the win.

Matt Breida ran for 101 yards and scored two TDs for the 49ers (2-8).