Two vehicles crashed at 409 N. Main St., Chicora, Saturday morning, landing one vehicle on its side and closing Route 68 through the borough.
One driver was flown to UPMC Presbyterian, while the other driver was transported by ambulance to Butler Memorial Hospital.
A pedestrian walking along the road was also clipped by one of the vehicles, but was uninjured.
The accident occurred at 8:27 a.m. There is no information available about the condition of the drivers or whether any charges will be filed.