NEW YORK — Before they stepped on court, there was nothing to suggest Andy Murray would have any trouble against Adrian Mannarino in the U.S. Open’s second round.

Murray, after all, is seeded No. 3 and owns two major championships.

Murray put together his eighth career comeback from a two-set deficit and beat Mannarino 5-7, 4-6, 6-1, 6-3, 6-1.

“He was looking for his rhythm,” Mannarino said.