BROOKVILLE — Have your game program handy.

Karns City and Brookville stand to use a lot of players — some new — when they clash at Brookville High School for a 7 p.m. kickoff Friday night.

Brookville, coming off a 2-8 season, has a new coach in Scott Park and a new offense to go with it.

The Raiders will feature a power running game as well as some veer.

Or so Park says.

“The first game is always tough because you just don't know,” said Karns City coach Ed Conto. “You just don't know if everything you've seen from the two weeks of scrimmages is going to be thrown out the window.”

The Gremlins have a history of using a slew of players and the season opener Friday will be no different.

Conto said he used a slew of substitutions during the scrimmage season.

“I saw a lot of improvement from Friday's scrimmage to practice,” Conto said. “The pieces are starting to fall into place.”

Conto still hasn't decided on a starting quarterback, however, between Cullen Williams and Jacob King.

Last year, Conto rotated QBs and he may do that again.

“We're watching every day and as soon as someone jumps out, it's still up in the air,” Conto said. “They're both working hard.”

Park inherits a traditionally strong Class AA team from long-time coach Chris Dworek.

There is talent on the roster in quarterback Seth Ray and receiver/linebacker Logan Thrush.

Breaking in his young talent against Karns City in the opener is not ideal, Park said.

“But, you know, they're a double-A school and we're a double-A school, so we have to play some time. These kids have worked hard and they have bought into something new and that isn't always an easy thing to do.”

Perry at Slippery Rock

7 p.m. Friday

What to look for: SR will start junior Bailey Mertens at QB. ... The Rockets ground game has amassed 8,447 yards the last two seasons. ... Perry was 3-6 last season but has a new coach in Craig Aguglia, who hopes to bring the Commodores back to prominence after two disappointing seasons.

Moniteau at Punxsutawney

7 p.m. Friday

What to look for: The Warriors are expecting big things from new QB Derek Boben and new TB Wyatt Ifft. ... Boben threw for 199 yards and 2 TDs in limited action last season and Ifft rushed for 279 yards on 53 carries last year.

Grove City at Wilmington 7 p.m. Friday

What to look for: Grove City won its final two games last season to finish 2-8. ... Eagles QB Kameron Patterson threw for 1,777 yards and 22 TDs last season. ... Wilmington coach Terry Verelli leads all District 10 coaches in victories with 282.

Freeport at Shady Side Academy

7 p.m. Friday

What to look for: The Indians have won two straight in the series, but Freeport holds an 11-10 edge all-time. ... Yellowjackets senior WRs Dylan and Brandon Hochbein combined for 83 catches last season.

Northgate at CW North Catholic

7 p.m. Friday

What to look for: Junior RB Mario Latronica, who rushed for 712 yards last year, will step into a starring role for North Catholic. ... Erick Taylor will take over at QB for the Trojans.

Keystone at Union

7 p.m. Friday

What to look for: Cole Morris will make his first start under center for Union. Morris was 3-for-13 for 81 yards and 1 TD as a backup last season. ... The Golden Knights beat the Panthers 14-8 in last year's opener.

Clarion at A-C Valley

7 p.m., Friday

What to look for: Clarion head coach Larry Wiser is 10 wins shy of 200 in his career, entering this season with a record of 190-86-1. ... A-C Valley has not defeated the Bobcats since a 22-6 decision in 1998.

Summit Academy at Highlands

7 p.m. Friday

What to look for: The Knights are making their return to the Allegheny Conference after going 0-9 as a member of the Midwestern Conference last year. ... This is the first meeting between the two schools.