SAN DIEGO — Bobby Abreu was annoyed by lack of speed in Odrisamer Despaigne’s curveball and playfully decided to complain to plate umpire Chris Guccione.

“It was the highlight of the day,” Padres catcher Yasmani Grandal said. “He looked back at the umpire and said we were cheating, and the umpire started laughing.”

Despaigne came within four outs of the first no-hitter in San Diego’s 46-year major league history on Sunday, and the Padres beat the New York Mets 2-1 on Seth Smith’s run-scoring infield single in the ninth.

Making his fifth major league start, Despaigne didn’t allow a hit until Daniel Murphy doubled to left-center with two outs in the eighth.

“I thought I threw him a pretty good pitch,” Despaigne said through Grandal, who served as his translator. “I did great with all my pitches, attacking after getting the first strike.”

San Diego, the only active major league franchise without a no-hitter, was playing its 7,264th regular-season game and has played 34 more in the postseason.

The Mets were the only other active big league team without a no-hitter before Johan Santana pitched one against St. Louis in June 2012 during New York’s 8,020th regular-season game.

Despaigne, a 27-year-old Cuban right-hander signed as a minor league free agent on May 2, allowed one run and two hits in 7 2-3 innings with five strikeouts and three walks. He threw 123 pitches and lowered his ERA to 1.31.

“I thought he was throwing well enough to think, `Hey, it could happen,” Padres manager Bud Black said. “He had all four pitches working from different angles. His stuff was good enough to keep them off-balance.”

His was the longest no-hit bid by a single Padres pitcher since Sept. 7, 2008, when Chris Young allowed a two-out home run in the eighth to Milwaukee’s Gabe Kapler.

“I think we saw in the fourth time through the lineup we started having better at-bats,” Murphy said. “I got the base hit, David got the base hit. So the next time we’ll have a better idea.”

Despaigne threw a fastball above 90 mph, a slider in the 80s, a changeup in the 70s and a curveball in the 60s.

“When you vary your speeds from 65-to-93, that’s tough to get a good pitch to hit,” Mets manager Terry Collins said.