LOS ANGELES — In the blink of an eye, late-night TV is shifting from a white men's club to the start of a rainbow coalition.

Wanda Sykes' weekly Fox comedy show debuts 11 p.m. Saturday, followed by George Lopez's four-night-a-week talk show on TBS, starting 11 p.m. Monday. They join "The Mo'Nique Show" on BET.

Lopez is counting on an audience hungry for something different — as in the first Hispanic to host a nighttime talk show on a major network, cable or broadcast.

Sykes is the first black late-night host since the late 1990s, when celebrities Earvin "Magic" Johnson and Keenan Ivory Wayans tried and failed to follow in Arsenio Hall's successful 1989-94 footsteps.

"There's a huge percentage of people not watching late-night TV at all," Lopez said, figuring that the shows headlined by hosts including David Letterman, Conan O'Brien and Jimmy Kimmel draw from roughly the same audience pool.

For people of color, the actor and comedian said, "I don't think a lot of their needs are met with the current talk shows. I would pull a different audience."

Shari Anne Brill, an analyst with media-buyer Carat USA in New York, echoes Lopez's assertion.

"There is a huge, growing multicultural population in this country, and the current late-night fare doesn't really take them into account," she said.

But neither Lopez nor Sykes are talking about practicing exclusionary TV. Lopez's ABC sitcom drew a cross-section of viewers, and Sykes said she expects her show to attract the same mixed crowd she gets at her stand-up appearances.

"Young, old, male, female, all races, gay, straight. I love the audience that I draw," Sykes said.

She rebuts the idea she got the job because of her gender, ethnicity or sexual orientation.

"I do understand the importance of being on a late-night talk show as a black, gay woman. But I've been at this for 20 years. I don't think they (networks) were saying, `Hey, it would be fun to get a black woman on late-night. Who fits that role?'

"I got this show in spite of being a black lesbian," she said, adding that viewers will tune in to see her or Lopez and not a type.

Eva Longoria-Parker, Ellen DeGeneres and Los Angeles Lakers basketball star Kobe Bryant are the scheduled debut night guests for Lopez. Sykes will welcome Mary Lynn Rajskub of "24," Daryl "Chill" Mitchell of "Brothers" and "The Amazing Race" host Phil Keoghan.